Chiefs at Bills: Week 12 preview, odds and injuries

Week 12 · Thu, Nov 26 · Highmark Stadium8:20 PM ET

at8:20 PMET · NBC

At a glanceUpdated Nov 10, 2026, 3:09 PM ET

The Kansas City Chiefs (6-2) visit the Buffalo Bills (7-1) on Thu, Nov 26, 8:20 PM ET at Highmark Stadium in Orchard Park, NY (Week 12, 2026 season), on NBC.

When and where is Chiefs vs Bills?

Thu, Nov 26, 8:20 PM ET at Highmark Stadium in Orchard Park, NY. TV: NBC.

Who is injured for Chiefs vs Bills?

Chiefs: Omarr Norman-Lott (DT, out, knee - acl), Jaylon Moore (OT, questionable, ankle), Mansoor Delane (CB, questionable, shoulder), Patrick Mahomes (QB, questionable, elbow), Peter Woods (DT, questionable, neck) and Xavier Worthy (WR, questionable, hamstring). Bills: Tyrell Shavers (WR, out, knee - acl), Alec Anderson (OT, questionable, ankle), Dion Dawkins (OT, questionable, ribs) and Greg Gaines (DT, questionable, calf).

Cite this page

Pigskin Nightly, “Chiefs at Bills: Week 12 preview”, https://pigskinnightly.com/games/2026-11-26-kc-at-buf (updated 2026-11-10).

How we calculate Plain-text version Report an error

Regular season through week 11 · rank out of 32

Where this game will be decided

1Chiefs pass protection vs Bills pass rush
The Chiefs' pass protection ranks 6th in sack rate (3.8% sacked, 290 dropbacks) against a Bills pass rush ranked 21st (5.2% of dropbacks, 328 dropbacks faced).
6thKC offense15 spots apart21stBUF defense
2Chiefs big-play offense vs Bills defense against big plays
The Chiefs' big-play offense ranks 4th in explosive-play rate (10.9%, 485 plays) against a Bills defense against big plays ranked 16th (9.5% allowed, 504 plays faced).
4thKC offense12 spots apart16thBUF defense

When the Chiefs have the ballEdge KC · +8 ranks

KC dropback offenseEPA per dropbackBUF pass defense

8th+0.16290 dropbacks

KC +8

+0.05 allowed328 dropbacks faced16th

KC run gameEPA per rushBUF run defense

2nd+0.09195 rushes

-0.11 allowed176 rushes faced8th

Dropbacks include sacks and scrambles; rushes are designed runs. What EPA measures.

When the Bills have the ballNo big edge

BUF dropback offenseEPA per dropbackKC pass defense

4th+0.25277 dropbacks

-0.01 allowed305 dropbacks faced10th

BUF run gameEPA per rushKC run defense

7th+0.00227 rushes

-0.16 allowed197 rushes faced6th

Third downNo big edge

KC third-down offensethird-down conversion rateBUF third-down defense

12th42.1%95 third downs

39.0% allowed100 third downs faced14th

BUF third-down offensethird-down conversion rateKC third-down defense

5th45.7%92 third downs

37.6% allowed109 third downs faced10th

Conversions are third-down snaps that gained a first down or scored.

Red zoneEdge KC · +11 ranks

KC red-zone offensered-zone touchdown rateBUF red-zone defense

10th63%30 trips

KC +11

63% allowed30 trips faced21st

BUF red-zone offensered-zone touchdown rateKC red-zone defense

9th65%34 trips

38% allowed21 trips faced3rd

A trip is a drive with at least one snap inside the opponent's 20; the rate is trips that ended in an offensive touchdown. Small samples swing fast here.

Explosive playsEdge KC · +12 ranks

KC big-play offenseexplosive-play rateBUF defense against big plays

4th10.9%485 plays

KC +12

9.5% allowed504 plays faced16th

BUF big-play offenseexplosive-play rateKC defense against big plays

1st13.5%504 plays

7.6% allowed502 plays faced7th

Completions of 20+ yards and runs of 10+, per snap. Definition.

Pressure & sacksEdge KC · +15 ranks

KC pass protectionsack rateBUF pass rush

6th3.8% sacked290 dropbacks

KC +15

5.2% of dropbacks328 dropbacks faced21st

BUF pass protectionsack rateKC pass rush

18th6.1% sacked277 dropbacks

BUF +13

4.6% of dropbacks305 dropbacks faced31st

Sacks per dropback. The public play-by-play has no pressure charting, so this is the sack side of it only.

TurnoversEdge KC · +9 ranks

KC ball securityturnovers per gameBUF takeaway defense

5th0.8 giveaways a game8 games

1.5 takeaways a game8 games5th

BUF ball securityturnovers per gameKC takeaway defense

23rd1.5 giveaways a game8 games

KC +9

1.3 takeaways a game8 games14th

Interceptions and lost fumbles on offensive snaps, per game. Turnover rates are among the least stable numbers in football.

AbsencesKC 0 · BUF 0 regulars out or doubtful

Chiefs6 listed

0 of them are regulars ruled out or doubtful (60%+ of their unit's snaps across 3+ weeks on the field).

QPatrick MahomesQB99% offense · 8 wk
QJaylon MooreOT87% offense · 7 wk
QXavier WorthyWR83% offense · 8 wk
QMansoor DelaneCB79% defense · 5 wk
OUTOmarr Norman-LottDTno snaps
QPeter WoodsDTno snaps

Bills4 listed

0 of them are regulars ruled out or doubtful (60%+ of their unit's snaps across 3+ weeks on the field).

QDion DawkinsOT99% offense · 7 wk
QGreg GainesDT32% defense · 6 wk
OUTTyrell ShaversWRno snaps
QAlec AndersonOTno snaps

Snap share is the average of the weeks each player was on the field this season. Full injury report ↓

Rest & travelSame rest · KC travels 858 mi

AwayChiefs

4days since last game

858miles to get here

1time zones

Last: Sun wk 11 vs ARI · 8,895 mi flown this season

Thursday after Sunday

Rest edgeEvensame restTravel gap 858 mi

HomeBills

4days since last game

0miles · home

0time zones

Last: Sun wk 11 vs MIA · 12,423 mi flown this season

Thursday after Sunday

League splits for these situations ↓

Sample: KC 8 games, 485 offensive and 502 defensive plays · BUF 8 games, 504 offensive and 504 defensive plays. Rank 1 is the best offense or the best defense in each stat. Keys are the largest rank gaps (12+ spots) between an offense and the defense it faces, one per stat. Ranks are not schedule-adjusted.

Season to date · rank out of 32