# Vikings at 49ers: Week 11 preview

> The Minnesota Vikings (6-2) visit the San Francisco 49ers (7-1) on Sun, Nov 22, 8:20 PM ET at Estadio Banorte in Mexico City (Week 11, 2026 season), on NBC. Betting line: SF -3.5, over/under 46.5.

- Source: https://pigskinnightly.com/games/2026-11-22-min-at-sf
- Publisher: Pigskin Nightly (https://pigskinnightly.com)
- Updated: 2026-11-11T02:51:30.974Z
- Method: https://pigskinnightly.com/methodology
- Please cite as: Pigskin Nightly, "Vikings at 49ers: Week 11 preview", https://pigskinnightly.com/games/2026-11-22-min-at-sf

## Questions and answers

### When and where is Vikings vs 49ers?

Sun, Nov 22, 8:20 PM ET at Estadio Banorte in Mexico City. TV: NBC.

### Who is favored in Vikings vs 49ers?

The line is SF -3.5 with an over/under of 46.5 (DraftKings).

### Who is injured for Vikings vs 49ers?

Vikings: Kyler Murray (QB, doubtful, hamstring), Jauan Jennings (WR, questionable, calf), Theo Jackson (S, questionable) and Tyrion Ingram-Dawkins (DE, questionable, ankle). 49ers: Brandon Aiyuk (WR, out, personal), Deebo Samuel Sr. (WR, questionable, hamstring), Deommodore Lenoir (CB, questionable, foot), Mike Evans (WR, questionable, achilles) and Renardo Green (CB, questionable, back).