# 49ers at Cowboys: Week 10 preview

> The San Francisco 49ers (7-1) visit the Dallas Cowboys (4-5) on Sun, Nov 15, 4:25 PM ET at AT&T Stadium in Arlington, TX (Week 10, 2026 season), on Fox. Betting line: SF -3.5, over/under 55.5.

- Source: https://pigskinnightly.com/games/2026-11-15-sf-at-dal
- Publisher: Pigskin Nightly (https://pigskinnightly.com)
- Updated: 2026-11-10T22:53:23.613Z
- Method: https://pigskinnightly.com/methodology
- Please cite as: Pigskin Nightly, "49ers at Cowboys: Week 10 preview", https://pigskinnightly.com/games/2026-11-15-sf-at-dal

## Questions and answers

### When and where is 49ers vs Cowboys?

Sun, Nov 15, 4:25 PM ET at AT&T Stadium in Arlington, TX. TV: Fox.

### Who is favored in 49ers vs Cowboys?

The line is SF -3.5 with an over/under of 55.5 (DraftKings).

### Who is injured for 49ers vs Cowboys?

49ers: Brandon Aiyuk (WR, out, personal), Deebo Samuel Sr. (WR, questionable, hamstring), Deommodore Lenoir (CB, questionable, foot), Mike Evans (WR, questionable, achilles) and Renardo Green (CB, questionable, back). Cowboys: Jake Ferguson (TE, out, knee), P.J. Locke (S, out, concussion), Tyler Goodson (RB, out, knee - acl + mcl), DeMarvion Overshown (LB, questionable, hamstring), Donovan Ezeiruaku (LB, questionable, ankle) and George Pickens (WR, questionable, hamstring) (plus 4 more).